RBM28 Antibody
Product Specifications
Background
The protein encoded by this gene is a specific nucleolar component of the spliceosomal small nuclear ribonucleoprotein (snRNP) complexes . It specifically associates with U1, U2, U4, U5, and U6 small nuclear RNAs (snRNAs), possibly coordinating their transition through the nucleolus. Mutation in this gene causes alopecia, progressive neurological defects, and endocrinopathy (ANE syndrome), a pleiotropic and clinically heterogeneous disorder. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
NCBI Gene ID
55131
Swiss Prot
Q9NW13
Accession Number
Q9NW13
Host
Rabbit
Reactivity
Human
Immunogen
This RBM28 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 62-91 amino acids from the N-terminal region of human RBM28.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
86 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
RBM28
NCBI Official Name
RNA-binding protein 28
NCBI Organism
Homo sapiens
Background Reference 01
Spiegel, R., et al. Eur. J. Endocrinol. 162 (6) :1021-1025 (2010)
Background Reference 02
Nousbeck, J., et al. Am. J. Hum. Genet. 82 (5) :1114-1121 (2008)
Background Reference 03
Damianov, A., et al. Biol. Chem. 387 (10-11), 1455-1460 (2006) :
Background Reference 04
Andersen, J.S., et al. Nature 433 (7021) :77-83 (2005)
Other Product Names
RNA-binding protein 28, RNA-binding motif protein 28, RBM28
Tested Applications
WB
Protein ID
55976611
Physical Properties
Liquid
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