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RBM28 Antibody

Product Specifications

Background

The protein encoded by this gene is a specific nucleolar component of the spliceosomal small nuclear ribonucleoprotein (snRNP) complexes . It specifically associates with U1, U2, U4, U5, and U6 small nuclear RNAs (snRNAs), possibly coordinating their transition through the nucleolus. Mutation in this gene causes alopecia, progressive neurological defects, and endocrinopathy (ANE syndrome), a pleiotropic and clinically heterogeneous disorder. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

NCBI Gene ID

55131

Swiss Prot

Q9NW13

Accession Number

Q9NW13

Host

Rabbit

Reactivity

Human

Immunogen

This RBM28 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 62-91 amino acids from the N-terminal region of human RBM28.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

86 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

RBM28

NCBI Official Name

RNA-binding protein 28

NCBI Organism

Homo sapiens

Background Reference 01

Spiegel, R., et al. Eur. J. Endocrinol. 162 (6) :1021-1025 (2010)

Background Reference 02

Nousbeck, J., et al. Am. J. Hum. Genet. 82 (5) :1114-1121 (2008)

Background Reference 03

Damianov, A., et al. Biol. Chem. 387 (10-11), 1455-1460 (2006) :

Background Reference 04

Andersen, J.S., et al. Nature 433 (7021) :77-83 (2005)

Other Product Names

RNA-binding protein 28, RNA-binding motif protein 28, RBM28

Tested Applications

WB

Protein ID

55976611

Physical Properties

Liquid

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