RHEBL1 Antibody

Product Specifications

Background

RHEBL1 binds GTP and exhibits intrinsic GTPase activity. May activate NF-kappa-B-mediated gene transcription. Promotes signal transduction through FRAP1, activates RPS6KB1, and is a downstream target of the small GTPase-activating proteins TSC1 and TSC2.

NCBI Gene ID

121268

Swiss Prot

Q8TAI7

Accession Number

Q8TAI7

Host

Rabbit

Reactivity

Mouse

Immunogen

This RHEBL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 17-45 amino acids from the N-terminal region of human RHEBL1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

21 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

RHEBL1

NCBI Official Name

GTPase RhebL1

NCBI Organism

Homo sapiens

Background Reference 01

Yuan, J., et al. Mol. Biol. Rep. 32 (4) :205-214 (2005)

Background Reference 02

Tee, A.R., et al. FEBS Lett. 579 (21) :4763-4768 (2005)

Background Reference 03

Barrios-Rodiles, M., et al. Science 307 (5715) :1621-1625 (2005)

Background Reference 04

Tabancay, A.P. Jr., et al. J. Biol. Chem. 278 (41) :39921-39930 (2003)

Other Product Names

GTPase RhebL1, Ras homolog enriched in brain like-1 c, RhebL1c, Ras homolog enriched in brain-like protein 1, Rheb-like protein 1, Rheb2, RHEBL1

Tested Applications

Protein ID

74730357

Physical Properties

Liquid

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