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RPS4Y1 Antibody

Product Specifications

Background

Cytoplasmic ribosomes, organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes ribosomal protein S4, a component of the 40S subunit. Ribosomal protein S4 is the only ribosomal protein known to be encoded by more than one gene, namely this gene and ribosomal protein S4, X-linked (RPS4X) . The 2 isoforms encoded by these genes are not identical, but are functionally equivalent. Ribosomal protein S4 belongs to the S4E family of ribosomal proteins. It has been suggested that haploinsufficiency of the ribosomal protein S4 genes plays a role in Turner syndrome; however, this hypothesis is controversial. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.

NCBI Gene ID

6192

Swiss Prot

P22090

Accession Number

P22090

Host

Rabbit

Reactivity

Human

Immunogen

This RPS4Y1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 76-105 amino acids from the Central region of human RPS4Y1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Chicken, Xenopus

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

29 kDa

Fragment

Rabbit Ig

Symbol

RPS4Y1

NCBI Official Name

40S ribosomal protein S4, Y isoform 1

NCBI Organism

Homo sapiens

Background Reference 01

Agate, R.J., et al. Mol. Biol. Evol. 21 (2) :384-396 (2004)

Background Reference 02

Vawter, M.P., et al. Neuropsychopharmacology 29 (2) :373-384 (2004)

Background Reference 03

Kapp, L.D., et al. Annu. Rev. Biochem. 73, 657-704 (2004) :

Background Reference 04

Skaletsky, H., et al. Nature 423 (6942) :825-837 (2003)

Other Product Names

40S ribosomal protein S4, Y isoform 1, RPS4Y1, RPS4Y

Tested Applications

WB, IHC-P, Flow

Protein ID

133948

Physical Properties

Liquid

Frequently Asked Questions

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