XYLT1 Antibody

Product Specifications

Background

This locus encodes a xylosyltransferase enzyme. The encoded protein catalyzes transfer of UDP-xylose to serine residues of an acceptor protein substrate. This transfer reaction is necessary for biosynthesis of glycosaminoglycan chains. Mutations in this gene have been associated with increased severity of pseudoxanthoma elasticum.

NCBI Gene ID

64131

Swiss Prot

Q86Y38

Accession Number

Q86Y38

Host

Rabbit

Reactivity

Human

Immunogen

This XYLT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 126-155 amino acids from the N-terminal region of human XYLT1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

108 kDa

Fragment

Rabbit Ig

Symbol

XYLT1

NCBI Official Name

Xylosyltransferase 1

NCBI Organism

Homo sapiens

Background Reference 01

Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :

Background Reference 02

Muller, B., et al. J. Biol. Chem. 284 (45) :30775-30782 (2009)

Background Reference 03

Ponighaus, C., et al. Am. J. Hypertens. 22 (4) :432-436 (2009)

Background Reference 04

Ambrosius, M., et al. Clin. Biochem. 42 (1-2), 1-4 (2009) :

Other Product Names

Xylosyltransferase 1, Peptide O-xylosyltransferase 1, Xylosyltransferase I, XT-I, XylT-I, XYLT1, XT1

Tested Applications

WB, Flow

Protein ID

71164803

Physical Properties

Liquid

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