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RPL15 Antibody

Product Specifications

Background

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L15E family of ribosomal proteins. It is located in the cytoplasm. This gene shares sequence similarity with the yeast ribosomal protein YL10 gene. Although this gene has been referred to as RPL10, its official symbol is RPL15. This gene has been shown to be overexpressed in some esophageal tumors compared to normal matched tissues. Transcript variants utilizing alternative polyA signals exist. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.

NCBI Gene ID

6138

Swiss Prot

P61313

Accession Number

P61313

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This RPL15 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 21-50 amino acids from the N-terminal region of human RPL15.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine, Monkey, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

24 kDa

Fragment

Rabbit Ig

Symbol

RPL15

NCBI Official Name

60S ribosomal protein L15

NCBI Organism

Homo sapiens

Background Reference 01

Wheeler, H.E., et al. PLoS Genet. (10), E1000685 (2009) :

Background Reference 02

Wang, H., et al. BMC Cancer 6, 91 (2006) :

Background Reference 03

Andersen, J.S., et al. Nature 433 (7021) :77-83 (2005)

Background Reference 04

Kapp, L.D., et al. Annu. Rev. Biochem. 73, 657-704 (2004) :

Other Product Names

60S ribosomal protein L15, RPL15, EC45

Tested Applications

WB, IHC-P, Flow

Protein ID

47117726

Physical Properties

Liquid

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