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SYK Antibody

Product Specifications

Background

This gene encodes a member of the family of non-receptor type Tyr protein kinases. This protein is widely expressed in hematopoietic cells and is involved in coupling activated immunoreceptors to downstream signaling events that mediate diverse cellular responses, including proliferation, differentiation, and phagocytosis. It is thought to be a modulator of epithelial cell growth and a potential tumour suppressor in human breast carcinomas. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].

NCBI Gene ID

6850

Swiss Prot

P43405

Accession Number

P43405

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This SYK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 268-305 amino acids from human SYK.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Immunology, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Pig

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=56-631

Calculated Molecular Weight

72 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

SYK

NCBI Official Name

Tyrosine-protein kinase SYK

NCBI Organism

Homo sapiens

Background Reference 01

Thomas, D.H., et al. Blood 116 (14) :2570-2578 (2010)

Background Reference 02

Poeck, H., et al. J. Mol. Med. 88 (8) :745-752 (2010)

Background Reference 03

Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :

Background Reference 04

Pechloff, K., et al. J. Exp. Med. 207 (5) :1031-1044 (2010)

Other Product Names

Tyrosine-protein kinase SYK, Spleen tyrosine kinase, p72-Syk, SYK

Tested Applications

WB

Protein ID

1174527

Physical Properties

Liquid

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