HRC Antibody

Product Specifications

Background

This gene encodes a luminal sarcoplasmic reticulum protein identified by its ability to bind low-density lipoprotein with high affinity. The protein interacts with the cytoplasmic domain of triadin, the main transmembrane protein of the junctional sarcoplasmic reticulum (SR) of skeletal muscle. The protein functions in the regulation of releasable calcium into the SR.

NCBI Gene ID

3270

Swiss Prot

P23327

Accession Number

P23327

Host

Rabbit

Reactivity

Human

Immunogen

This HRC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 277-306 amino acids from the Central region of human HRC.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

80 kDa

Fragment

Rabbit Ig

Symbol

HRC

NCBI Official Name

Sarcoplasmic reticulum histidine-rich calcium-binding protein

NCBI Organism

Homo sapiens

Background Reference 01

Arvanitis, D.A., et al. Eur. Heart J. 29 (20) :2514-2525 (2008)

Background Reference 02

Arvanitis, D.A., et al. Am. J. Physiol. Heart Circ. Physiol. 293 (3), H1581-H1589 (2007) :

Background Reference 03

Fan, G.C., et al. Am. J. Physiol. Heart Circ. Physiol. 287 (4), H1705-H1711 (2004) :

Background Reference 04

Anderson, J.P., et al. Mol. Cell. Biol. 24 (9) :3757-3768 (2004)

Other Product Names

Sarcoplasmic reticulum histidine-rich calcium-binding protein, HRC, HCP

Tested Applications

WB, IHC-P

Protein ID

134873

Physical Properties

Liquid

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