RIC3 Antibody
Product Specifications
Background
RIC3 is a protein associated with nicotinic acetylcholine receptors (nAChRs), neurotransmitter-gated ion channels expressed at the neuromuscular junction and within the central and peripheral nervous systems, that can enhance functional expression of multiple nAChR subtypes (Lansdell et al., 2005 [PubMed 16120769]) .[supplied by OMIM].
NCBI Gene ID
79608
Swiss Prot
Q7Z5B4
Accession Number
Q7Z5B4
Host
Rabbit
Reactivity
Human
Immunogen
This RIC3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 313-341 amino acids from the C-terminal region of human RIC3.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
41 kDa
Fragment
Rabbit Ig
Symbol
RIC3
NCBI Official Name
Protein RIC-3
NCBI Organism
Homo sapiens
Background Reference 01
Walstab, J., et al. J. Biol. Chem. 285 (35) :26956-26965 (2010)
Background Reference 02
Bailey, S.D., et al. Diabetes Care (2010) In press :
Background Reference 03
Talmud, P.J., et al. Am. J. Hum. Genet. 85 (5) :628-642 (2009)
Background Reference 04
Seredenina, T., et al. Biosci. Rep. 28 (6) :299-306 (2008)
Other Product Names
Protein RIC-3, Resistant to inhibitor of cholinesterase 3, RIC3
Tested Applications
WB, IHC-P
Protein ID
74713638
Physical Properties
Liquid
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