ONECUT1 Antibody

Product Specifications

Background

ONECUT1 is a transcriptional activator. It binds the consensus sequence 5'-DHWATTGAYTWWD-3' on a variety of gene promoters such as those of HNF3B and TTR. It is important for liver genes transcription.

NCBI Gene ID

3175

Swiss Prot

Q9UBC0

Accession Number

Q9UBC0

Host

Rabbit

Reactivity

Human

Immunogen

This ONECUT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 356-385 amino acids from the C-terminal region of human ONECUT1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Obesity, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

51 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

ONECUT1

NCBI Official Name

Hepatocyte nuclear factor 6

NCBI Organism

Homo sapiens

Background Reference 01

Lee, Y.S., et al. Biochem. J. 413 (3) :559-569 (2008)

Background Reference 02

Jiang, X., et al. Oncol. Rep. 19 (1) :157-163 (2008)

Background Reference 03

Lehner, F., et al. FASEB J. 21 (7) :1445-1462 (2007)

Background Reference 04

Rausa, F.M. III, et al. J. Biol. Chem. 279 (41) :43070-43076 (2004)

Other Product Names

Hepatocyte nuclear factor 6, HNF-6, One cut domain family member 1, One cut homeobox 1, ONECUT1, HNF6, HNF6A

Tested Applications

Protein ID

13627184

Physical Properties

Liquid

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