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MAT1A Antibody

Product Specifications

Background

This gene catalyzes a two-step reaction that involves the transfer of the adenosyl moiety of ATP to methionine to form S-adenosylmethionine and tripolyphosphate, which is subsequently cleaved to PPi and Pi. S-adenosylmethionine is the source of methyl groups for most biological methylations. The encoded protein is found as a homotetramer (MAT I) or a homodimer (MAT III) whereas a third form, MAT II (gamma), is encoded by the MAT2A gene. Mutations in this gene are associated with methionine adenosyltransferase deficiency.

NCBI Gene ID

4143

Swiss Prot

Q00266

Accession Number

Q00266

Host

Rabbit

Reactivity

Human

Immunogen

This MAT1A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 107-136 amino acids from the N-terminal region of human MAT1A.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse, Rat, Bovine

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=56-593

Calculated Molecular Weight

44 kDa

Fragment

Rabbit Ig

Symbol

MAT1A

NCBI Official Name

S-adenosylmethionine synthase isoform type-1

NCBI Organism

Homo sapiens

Background Reference 01

Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)

Background Reference 02

Wu, S.M., et al. Cell. Mol. Life Sci. 67 (11) :1831-1843 (2010)

Background Reference 03

Lai, C.Q., et al. Am. J. Clin. Nutr. 91 (5) :1377-1386 (2010)

Background Reference 04

Joslyn, G., et al. Alcohol. Clin. Exp. Res. 34 (5) :800-812 (2010)

Other Product Names

S-adenosylmethionine synthase isoform type-1, AdoMet synthase 1, Methionine adenosyltransferase 1, MAT 1, Methionine adenosyltransferase I/III, MAT-I/III, MAT1A, AMS1, MATA1

Tested Applications

WB, IHC-P

Protein ID

417297

Physical Properties

Liquid

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