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STAMBP Antibody

Product Specifications

Background

Cytokine-mediated signal transduction in the JAK-STAT cascade requires the involvement of adaptor molecules. One such signal-transducing adaptor molecule contains an SH3 domain that is required for induction of MYC and cell growth. The protein encoded by this gene binds to the SH3 domain of the signal-transducing adaptor molecule, and plays a critical role in cytokine-mediated signaling for MYC induction and cell cycle progression. Multiple alternatively spliced transcript variants encoding the same protein isoform have been found for this gene.

NCBI Gene ID

10617

Swiss Prot

O95630

Accession Number

O95630

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This STAMBP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 355-383 amino acids from the C-terminal region of human STAMBP.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

48 kDa

Fragment

Rabbit Ig

Symbol

STAMBP

NCBI Official Name

STAM-binding protein

NCBI Organism

Homo sapiens

Background Reference 01

Sierra, M.I., et al. J. Biol. Chem. 285 (18) :13990-14004 (2010)

Background Reference 02

Hasdemir, B., et al. J. Biol. Chem. 284 (41) :28453-28466 (2009)

Background Reference 03

Venkatesan, K., et al. Nat. Methods 6 (1) :83-90 (2009)

Background Reference 04

Wang, P., et al. BMC Genomics 10, 518 (2009) :

Other Product Names

STAM-binding protein, 3419-, Associated molecule with the SH3 domain of STAM, Endosome-associated ubiquitin isopeptidase, STAMBP, AMSH

Tested Applications

WB, IHC-P

Physical Properties

Liquid

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