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GRXCR1 Antibody

Product Specifications

Background

This gene is one of 60 loci associated with autosomal-recessive nonsyndromic hearing impairment. This gene encodes a protein which contains GRX-like domains; these domains play a role in the S-glutathionylation of proteins and may be involved in actin organization in hair cells.

NCBI Gene ID

389207

Swiss Prot

A8MXD5

Accession Number

A8MXD5

Host

Rabbit

Reactivity

Mouse

Immunogen

This GRXCR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 83-112 amino acids from the Central region of human GRXCR1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

32 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

GRXCR1

NCBI Official Name

Glutaredoxin domain-containing cysteine-rich protein 1

NCBI Organism

Homo sapiens

Background Reference 01

Schraders, M., et al. Am. J. Hum. Genet. 86 (2) :138-147 (2010)

Background Reference 02

Hillier, L.W., et al. Nature 434 (7034) :724-731 (2005)

Background Reference 03

Harrington, J.J., et al. Nat. Biotechnol. 19 (5) :440-445 (2001)

Other Product Names

Glutaredoxin domain-containing cysteine-rich protein 1, GRXCR1, DFNB25

Tested Applications

WB

Physical Properties

Liquid

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