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GABRA4 Antibody

Product Specifications

Background

GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified.

NCBI Gene ID

2557

Swiss Prot

P48169

Accession Number

P48169

Host

Rabbit

Reactivity

Human

Immunogen

This GABRA4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 333-361 amino acids from the Central region of human GABRA4.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

62 kDa

Fragment

Rabbit Ig

Symbol

GABRA4

NCBI Official Name

Gamma-aminobutyric acid receptor subunit alpha-4

NCBI Organism

Homo sapiens

Background Reference 01

Bailey, S.D., et al. Diabetes Care (2010) In press :

Background Reference 02

Ruano, G., et al. Pharmacogenomics 11 (7) :959-971 (2010)

Background Reference 03

Pinheiro, A.P., et al. Am. J. Med. Genet.Neuropsychiatr. Genet. 153B (5), 1070-1080 (2010) :

Background Reference 04

Talmud, P.J., et al. Am. J. Hum. Genet. 85 (5) :628-642 (2009)

Other Product Names

Gamma-aminobutyric acid receptor subunit alpha-4, GABA (A) receptor subunit alpha-4, GABRA4

Tested Applications

WB, Flow

Protein ID

206729865

Physical Properties

Liquid

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