MED8 Antibody

Product Specifications

Background

This gene encodes a protein that is one of more than 20 subunits of the mediator complex, first identified in S. cerevisiae, that is required for activation of transcription. The product of this gene also interacts with elongins B and C, and CUL2 and RBX1, to reconstitute a ubiquitin ligase. Two alternative transcripts encoding different isoforms have been described.

NCBI Gene ID

112950

Swiss Prot

Q96G25

Accession Number

Q96G25

Host

Rabbit

Reactivity

Human

Immunogen

This MED8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 95-122 amino acids from the Central region of human MED8.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Zebrafish, Mouse

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

29 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

MED8

NCBI Official Name

Mediator of RNA polymerase II transcription subunit 8

NCBI Organism

Homo sapiens

Background Reference 01

Leonard, V.H., et al. J. Virol. 80 (19) :9667-9675 (2006)

Background Reference 02

Wang, A.G., et al. Biochem. Biophys. Res. Commun. 345 (3) :1022-1032 (2006)

Background Reference 03

Sato, S., et al. Mol. Cell 14 (5) :685-691 (2004)

Background Reference 04

Tomomori-Sato, C., et al. J. Biol. Chem. 279 (7) :5846-5851 (2004)

Other Product Names

Mediator of RNA polymerase II transcription subunit 8, Activator-recruited cofactor 32 kDa component, ARC32, Mediator complex subunit 8, MED8

Tested Applications

Protein ID

31076772

Physical Properties

Liquid

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