MyoD1 Antibody

Product Specifications

Background

This gene encodes a nuclear protein that belongs to the basic helix-loop-helix family of transcription factors and the myogenic factors subfamily. It regulates muscle cell differentiation by inducing cell cycle arrest, a prerequisite for myogenic initiation. The protein is also involved in muscle regeneration. It activates its own transcription which may stabilize commitment to myogenesis.

NCBI Gene ID

4654

Swiss Prot

P15172

Accession Number

P15172

Host

Rabbit

Reactivity

Human

Immunogen

This MyoD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 211-240 amino acids from the Central region of human MyoD1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

35 kDa

Fragment

Rabbit Ig

Symbol

MYOD1

NCBI Official Name

Myoblast determination protein 1

NCBI Organism

Homo sapiens

Background Reference 01

Xynos, A., et al. Stem Cells 28 (5) :965-973 (2010)

Background Reference 02

Stuelsatz, P., et al. J. Biol. Chem. 285 (17) :12670-12683 (2010)

Background Reference 03

Hiraoka, S., et al. Hum. Pathol. 41 (1) :38-47 (2010)

Background Reference 04

Yerges, L.M., et al. J. Bone Miner. Res. 24 (12) :2039-2049 (2009)

Other Product Names

Myoblast determination protein 1, Class C basic helix-loop-helix protein 1, bHLHc1, Myogenic factor 3, Myf-3, MYOD1, BHLHC1, MYF3, MYOD

Tested Applications

WB, IF

Protein ID

209572729

Physical Properties

Liquid

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