RFX3 Antibody

Product Specifications

Background

This gene is a member of the regulatory factor X gene family, which encodes transcription factors that contain a highly-conserved winged helix DNA binding domain. The protein encoded by this gene is structurally related to regulatory factors X1, X2, X4, and X5. It is a transcriptional activator that can bind DNA as a monomer or as a heterodimer with other RFX family members. Two transcript variants encoding different isoforms have been described for this gene, and at least one of the variants utilizes alternative polyadenylation signals.

NCBI Gene ID

5991

Swiss Prot

P48380

Accession Number

P48380

Host

Rabbit

Reactivity

Human

Immunogen

This RFX3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 661-690 amino acids from the C-terminal region of human RFX3.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Monkey

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

84 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

RFX3

NCBI Official Name

Transcription factor RFX3

NCBI Organism

Homo sapiens

Background Reference 01

El Zein, L., et al. J. Cell. Sci. 122 (PT 17), 3180-3189 (2009) :

Background Reference 02

Humphray, S.J., et al. Nature 429 (6990) :369-374 (2004)

Background Reference 03

Maijgren, S., et al. Arch. Dermatol. Res. 295 (11) :482-489 (2004)

Background Reference 04

Nakayama, A., et al. J. Biol. Chem. 278 (1) :233-240 (2003)

Other Product Names

Transcription factor RFX3, Regulatory factor X 3, RFX3

Tested Applications

Protein ID

32172437

Physical Properties

Liquid

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