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MGAT4C Antibody

Product Specifications

Background

Glycosyltransferase that participates in the transfer of N-acetylglucosamine (GlcNAc) to the core mannose residues of N-linked glycans. Catalyzes the formation of the GlcNAcbeta1-4 branch on the GlcNAcbeta1-2Manalpha1-3 arm of the core structure of N-linked glycans. Essential for the production of tri-and tetra-antennary N-linked sugar chains (By similarity) . Does not catalyze the transfer of GlcNAc to the Manalpha1-6 arm to form GlcNAcBeta1-4Manalpha1-6 linkage ('GnT-VI' activity) .

NCBI Gene ID

25834

Swiss Prot

Q9UBM8

Accession Number

Q9UBM8

Host

Rabbit

Reactivity

Human

Immunogen

This MGAT4C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 303-332 amino acids from the C-terminal region of human MGAT4C.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Obesity, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Monkey, Mouse, Pig

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=56-542

Calculated Molecular Weight

56 kDa

Fragment

Rabbit Ig

Symbol

MGAT4C

NCBI Official Name

Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C

NCBI Organism

Homo sapiens

Background Reference 01

Rose, J. Phd, et al. Mol. Med. (2010) In press :

Background Reference 02

Trynka, G., et al. Gut 58 (8) :1078-1083 (2009)

Background Reference 03

Furukawa, T., et al. J. Hum. Genet. 44 (6) :397-401 (1999)

Background Reference 04

Thomas, B.A. Br. J. Dermatol. 80 (6), 413 (1968) :

Other Product Names

Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C, N-acetylglucosaminyltransferase IV homolog, hGnT-IV-H, N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase IVc, GlcNAc-T IVc, GnT-IVc, N-acetylglucosaminyltransferase IVc, UDP-N-acetylglucosamine: alpha-1,3-D-mannoside beta-1,4-N-acetylglucosaminyltransferase IVc, MGAT4C

Tested Applications

WB, IHC-P

Protein ID

296437368

Physical Properties

Liquid

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