ASS1 Antibody

Product Specifications

Background

The protein encoded by this gene catalyzes the penultimate step of the arginine biosynthetic pathway. There are approximately 10 to 14 copies of this gene including the pseudogenes scattered across the human genome, among which the one located on chromosome 9 appears to be the only functional gene for argininosuccinate synthetase. Mutations in the chromosome 9 copy of ASS cause citrullinemia. Two transcript variants encoding the same protein have been found for this gene.

NCBI Gene ID

445

Swiss Prot

P00966

Accession Number

P00966

Host

Rabbit

Reactivity

Human

Immunogen

This ASS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 281-310 amino acids from the C-terminal region of human ASS1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Obesity, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine, Chicken, Mouse, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

47 kDa

Fragment

Rabbit Ig

Symbol

ASS1

NCBI Official Name

Argininosuccinate synthase

NCBI Organism

Homo sapiens

Background Reference 01

Hozyasz, K.K., et al. Arch. Oral Biol. 55 (11) :861-866 (2010)

Background Reference 02

Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)

Background Reference 03

Kobayashi, E., et al. Mol. Cancer Ther. 9 (3) :535-544 (2010)

Background Reference 04

Tsai, W.B., et al. Mol. Cancer Ther. 8 (12) :3223-3233 (2009)

Other Product Names

Argininosuccinate synthase, Citrulline--aspartate ligase, ASS1, ASS

Tested Applications

WB, IHC-P, Flow

Protein ID

20141195

Physical Properties

Liquid

Curated Selection

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