HOXB3 Antibody
Product Specifications
Background
This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development. Increased expression of this gene is associated with a distinct biologic subset of acute myeloid leukemia (AML) .
NCBI Gene ID
3213
Swiss Prot
P14651
Accession Number
P14651
Host
Rabbit
Reactivity
Human
Immunogen
This HOXB3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 119-148 amino acids from the Central region of human HOXB3.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
44 kDa
Fragment
Rabbit Ig
Symbol
HOXB3
NCBI Official Name
Homeobox protein Hox-B3
NCBI Organism
Homo sapiens
Background Reference 01
Palakurthy, R.K., et al. Mol. Cell 36 (2) :219-230 (2009)
Background Reference 02
Ferrai, C., et al. Mol. Biol. Cell 20 (15) :3543-3551 (2009)
Background Reference 03
Chung, N., et al. Mol. Biol. Rep. 36 (2) :227-235 (2009)
Background Reference 04
Speleman, F., et al. Leukemia 19 (3) :358-366 (2005)
Other Product Names
Homeobox protein Hox-B3, Homeobox protein Hox-27, Homeobox protein Hox-2G, HOXB3, HOX2G
Tested Applications
WB, IHC-P
Protein ID
215274007
Physical Properties
Liquid
Curated Selection
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