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MLXIPL Antibody

Product Specifications

Background

This gene encodes a basic helix-loop-helix leucine zipper transcription factor of the Myc/Max/Mad superfamily. This protein forms a heterodimeric complex and binds and activates, in a glucose-dependent manner, carbohydrate response element (ChoRE) motifs in the promoters of triglyceride synthesis genes. The gene is deleted in Williams-Beuren syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at chromosome 7q11.23.

NCBI Gene ID

51085

Swiss Prot

Q9NP71

Accession Number

Q9NP71

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This MLXIPL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 624-653 amino acids from the C-terminal region of human MLXIPL.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Obesity

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

93 kDa

Fragment

Rabbit Ig

Symbol

MLXIPL

NCBI Official Name

Carbohydrate-responsive element-binding protein

NCBI Organism

Homo sapiens

Background Reference 01

Hu, M., et al. Pharmacogenet. Genomics 20 (10) :634-637 (2010)

Background Reference 02

Johansen, C.T., et al. Nat. Genet. 42 (8) :684-687 (2010)

Background Reference 03

Keebler, M.E., et al. Circ Cardiovasc Genet 3 (4) :358-364 (2010)

Background Reference 04

Chidambaram, M., et al. Metab. Clin. Exp. (2010) In press :

Other Product Names

Carbohydrate-responsive element-binding protein, ChREBP, Class D basic helix-loop-helix protein 14, bHLHd14, MLX interactor, MLX-interacting protein-like, WS basic-helix-loop-helix leucine zipper protein, WS-bHLH, Williams-Beuren syndrome chromosomal region 14 protein, MLXIPL, BHLHD14, MIO, WBSCR14

Tested Applications

WB, IHC-P

Protein ID

20140871

Physical Properties

Liquid

Frequently Asked Questions

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