MLXIPL Antibody
Product Specifications
Background
This gene encodes a basic helix-loop-helix leucine zipper transcription factor of the Myc/Max/Mad superfamily. This protein forms a heterodimeric complex and binds and activates, in a glucose-dependent manner, carbohydrate response element (ChoRE) motifs in the promoters of triglyceride synthesis genes. The gene is deleted in Williams-Beuren syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at chromosome 7q11.23.
NCBI Gene ID
51085
Swiss Prot
Q9NP71
Accession Number
Q9NP71
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This MLXIPL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 624-653 amino acids from the C-terminal region of human MLXIPL.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Obesity
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=56-508
Calculated Molecular Weight
93 kDa
Fragment
Rabbit Ig
Symbol
MLXIPL
NCBI Official Name
Carbohydrate-responsive element-binding protein
NCBI Organism
Homo sapiens
Background Reference 01
Hu, M., et al. Pharmacogenet. Genomics 20 (10) :634-637 (2010)
Background Reference 02
Johansen, C.T., et al. Nat. Genet. 42 (8) :684-687 (2010)
Background Reference 03
Keebler, M.E., et al. Circ Cardiovasc Genet 3 (4) :358-364 (2010)
Background Reference 04
Chidambaram, M., et al. Metab. Clin. Exp. (2010) In press :
Other Product Names
Carbohydrate-responsive element-binding protein, ChREBP, Class D basic helix-loop-helix protein 14, bHLHd14, MLX interactor, MLX-interacting protein-like, WS basic-helix-loop-helix leucine zipper protein, WS-bHLH, Williams-Beuren syndrome chromosomal region 14 protein, MLXIPL, BHLHD14, MIO, WBSCR14
Tested Applications
WB, IHC-P
Protein ID
20140871
Physical Properties
Liquid
Curated Selection
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