PEX14 Antibody
Product Specifications
Background
This gene encodes an essential component of the peroxisomal import machinery. The protein is integrated into peroxisome membranes with its C-terminus exposed to the cytosol, and interacts with the cytosolic receptor for proteins containing a PTS1 peroxisomal targeting signal. The protein also functions as a transcriptional corepressor and interacts with a histone deacetylase. A mutation in this gene results in one form of Zellweger syndrome.
NCBI Gene ID
5195
Swiss Prot
O75381
Accession Number
O75381
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This PEX14 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 121-150 amino acids from the Central region of human PEX14.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=56-506
Calculated Molecular Weight
41 kDa
Fragment
Rabbit Ig
Symbol
PEX14
NCBI Official Name
Peroxisomal membrane protein PEX14
NCBI Organism
Homo sapiens
Background Reference 01
Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010) Macgregor, S., et al. Hum. Mol. Genet. 19 (13) :2716-2724 (2010) Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) Talmud, P.J., et al. Am. J. Hum. Genet. 85 (5) :628-642 (2009) Shiozawa, K., et al. J. Biol. Chem. 284 (37) :25334-25342 (2009)
Other Product Names
Peroxisomal membrane protein PEX14, PTS1 receptor-docking protein, Peroxin-14, Peroxisomal membrane anchor protein PEX14, PEX14
Tested Applications
WB, Flow
Physical Properties
Liquid
Curated Selection
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