GDF15 Antibody
Product Specifications
Background
Bone morphogenetic proteins (e.g., BMP9; MIM 605120) are members of the transforming growth factor-beta (see TGFB1; MIM 190180) superfamily and regulate tissue differentiation and maintenance. They are synthesized as precursor molecules that are processed at a dibasic cleavage site to release C-terminal domains containing a characteristic motif of 7 conserved cysteines in the mature protein.
NCBI Gene ID
9518
Swiss Prot
Q99988
Accession Number
Q99988
Host
Rabbit
Reactivity
Human
Immunogen
This GDF15 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 51-79 amino acids from the N-terminal region of human GDF15.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=56-501
Calculated Molecular Weight
34 kDa
Fragment
Rabbit Ig
Symbol
GDF15
NCBI Official Name
Growth/differentiation factor 15
NCBI Organism
Homo sapiens
Background Reference 01
Anand, I.S., et al. Circulation 122 (14) :1387-1395 (2010)
Background Reference 02
Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)
Background Reference 03
Staff, A.C., et al. Gynecol. Oncol. 118 (3) :237-243 (2010)
Background Reference 04
Roth, P., et al. Clin. Cancer Res. 16 (15) :3851-3859 (2010)
Other Product Names
Growth/differentiation factor 15, GDF-15, Macrophage inhibitory cytokine 1, MIC-1, NSAID-activated gene 1 protein, NAG-1, NSAID-regulated gene 1 protein, NRG-1, Placental TGF-beta, Placental bone morphogenetic protein, Prostate differentiation factor, GDF15, MIC1, PDF, PLAB, PTGFB
Tested Applications
WB, IHC-P, Flow
Protein ID
313104195
Physical Properties
Liquid
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