IL6 Antibody
Product Specifications
Background
This gene encodes a cytokine that functions in inflammation and the maturation of B cells. The protein is primarily produced at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of this gene is implicated in a wide variety of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis.
NCBI Gene ID
3569
Swiss Prot
P05231
Accession Number
P05231
Host
Rabbit
Reactivity
Human
Immunogen
This IL6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 27-55 amino acids from the Central region of human IL6.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Immunology, Obesity, Neuroscience, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
24 kDa
Fragment
Rabbit Ig
Symbol
IL6
NCBI Official Name
Interleukin-6
NCBI Organism
Homo sapiens
Background Reference 01
Perez, A.B., et al. Hum. Immunol. 71 (11) :1135-1140 (2010)
Background Reference 02
Weng, X.M., et al. Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi 24 (1) :42-44 (2010)
Background Reference 03
Santhosh, S., et al. Trop Gastroenterol 31 (1) :30-33 (2010)
Background Reference 04
Gein, O.N., et al. Patol Fiziol Eksp Ter 1, 10-13 (2010) :
Other Product Names
Interleukin-6, IL-6, B-cell stimulatory factor 2, BSF-2, CTL differentiation factor, CDF, Hybridoma growth factor, Interferon beta-2, IFN-beta-2, IL6, IFNB2
Tested Applications
WB, IHC-P, Flow
Protein ID
124347
Physical Properties
Liquid
Frequently Asked Questions
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