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FASTK Antibody

Product Specifications

Background

The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase was shown to be activated rapidly during Fas-mediated apoptosis in Jurkat cells. In response to Fas receptor ligation, it phosphorylates TIA1, an apoptosis-promoting nuclear RNA-binding protein. The encoded protein is a strong inducer of lymphocyte apoptosis. Two transcript variants encoding different isoforms have been found for this gene. Other variants exist, but their full-length natures have not yet been determined.

NCBI Gene ID

10922

Swiss Prot

Q14296

Accession Number

Q14296

Host

Rabbit

Reactivity

Human

Immunogen

This FASTK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 395-424 amino acids from the C-terminal region of human FASTK.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=56-444

Calculated Molecular Weight

61 kDa

Fragment

Rabbit Ig

Symbol

FASTK

NCBI Official Name

Fas-activated serine/threonine kinase

NCBI Organism

Homo sapiens

Background Reference 01

Simarro, M., et al. J. Immunol. 184 (9) :5325-5332 (2010)

Background Reference 02

De Krom, M., et al. Biol. Psychiatry 65 (7) :625-630 (2009)

Background Reference 03

Simarro, M., et al. Proc. Natl. Acad. Sci. U.S.A. 104 (27) :11370-11375 (2007)

Background Reference 04

Wu, C., et al. Proteomics 7 (11) :1775-1785 (2007)

Other Product Names

Fas-activated serine/threonine kinase, FAST kinase, FASTK

Tested Applications

WB, IHC-P

Protein ID

13124202

Physical Properties

Liquid

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