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ZFYVE1 Antibody

Product Specifications

Background

The FYVE domain mediates the recruitment of proteins involved in membrane trafficking and cell signaling to phosphatidylinositol 3-phosphate (PtdIns (3) P) -containing membranes. This gene encodes a protein which contains two zinc-binding FYVE domains in tandem. This protein displays a predominantly Golgi, endoplasmic reticulum and vesicular distribution. Alternatively spliced transcript variants have been found for this gene, and they encode two isoforms with different sizes.

NCBI Gene ID

53349

Swiss Prot

Q9HBF4

Accession Number

Q9HBF4

Host

Rabbit

Reactivity

Human

Immunogen

This ZFYVE1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 145-173 amino acids from the N-terminal region of human ZFYVE1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

87 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

ZFYVE1

NCBI Official Name

Zinc finger FYVE domain-containing protein 1

NCBI Organism

Homo sapiens

Background Reference 01

Wan, D., et al. Proc. Natl. Acad. Sci. U.S.A. 101 (44) :15724-15729 (2004)

Background Reference 02

Heilig, R., et al. Nature 421 (6923) :601-607 (2003)

Background Reference 03

Krugmann, S., et al. Mol. Cell 9 (1) :95-108 (2002)

Background Reference 04

Ridley, S.H., et al. J. Cell. Sci. 114 (PT 22), 3991-4000 (2001) :

Other Product Names

Zinc finger FYVE domain-containing protein 1, Double FYVE-containing protein 1, SR3, Tandem FYVE fingers-1, ZFYVE1, DFCP1, KIAA1589, TAFF1, ZNFN2A1

Tested Applications

WB

Protein ID

34098716

Physical Properties

Liquid

Frequently Asked Questions

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