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FBXO15 Antibody

Product Specifications

Background

Members of the F-box protein family, such as FBXO15, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]) .[supplied by OMIM].

NCBI Gene ID

201456

Swiss Prot

Q8NCQ5

Accession Number

Q8NCQ5

Host

Rabbit

Reactivity

Human

Immunogen

This FBXO15 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 130-158 amino acids from the N-terminal region of human FBXO15.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Cell Cycle, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Monkey

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

57 kDa

Fragment

Rabbit Ig

Symbol

FBXO15

NCBI Official Name

F-box only protein 15

NCBI Organism

Homo sapiens

Background Reference 01

Lamesch, P., et al. Genomics 89 (3) :307-315 (2007)

Background Reference 02

Jin, J., et al. Genes Dev. 18 (21) :2573-2580 (2004)

Background Reference 03

Tokuzawa, Y., et al. Mol. Cell. Biol. 23 (8) :2699-2708 (2003)

Background Reference 04

Winston, J.T., et al. Curr. Biol. 9 (20) :1180-1182 (1999)

Other Product Names

F-box only protein 15, FBXO15, FBX15

Tested Applications

WB, IHC-P

Protein ID

384872371

Physical Properties

Liquid

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