Dok5 Antibody

Product Specifications

Background

DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK5 functions in RET-mediated neurite outgrowth and plays a positive role in activation of the MAP kinase pathway. Putative link with downstream effectors of RET in neuronal differentiation.

NCBI Gene ID

55816

Swiss Prot

Q9P104

Accession Number

Q9P104

Host

Rabbit

Reactivity

Human

Immunogen

This Dok5 antibody is generated from rabbits immunized with a recombinant protein (GST-tag removed) from human Dok5.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

35 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

DOK5

NCBI Official Name

Docking protein 5

NCBI Organism

Homo sapiens

Background Reference 01

Liu, X., et al.Am Acad Child Adolesc Psychiatry 49 (1) :33-41 (2010)

Background Reference 02

Tabassum, R., et al. BMC Med. Genet. 11, 35 (2010) :

Background Reference 03

Shi, L., et al. Cell. Signal. 18 (11) :1995-2003 (2006)

Background Reference 04

Cai, D., et al. J. Biol. Chem. 278 (28) :25323-25330 (2003)

Other Product Names

Docking protein 5, Downstream of tyrosine kinase 5, Insulin receptor substrate 6, IRS-6, IRS6, DOK5, C20orf180

Tested Applications

Protein ID

26393190

Physical Properties

Liquid

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

GA105064 1 Kit

Human UCP3 activation kit by CRISPRa

Ask

View Details

MBS6133758-01 0.1 mL

SIN3B (Paired Amphipathic Helix Protein Sin3b, Histone Deacetylase Complex Subunit Sin3b, KIAA0700, Transcriptional Corepressor Sin3b) (AP)

Ask

View Details

MBS6133758-02 5x 0.1 mL

SIN3B (Paired Amphipathic Helix Protein Sin3b, Histone Deacetylase Complex Subunit Sin3b, KIAA0700, Transcriptional Corepressor Sin3b) (AP)

Ask

View Details

LY416372 100 µg

LILRA3 (NM_006865) Human Over-expression Lysate

Ask

View Details

TA331950 100 µL

C20orf4 (AAR2) Rabbit Polyclonal Antibody

Ask

View Details

MG213739 10 µg

Olfr535 (NM_146954) Mouse Tagged ORF Clone

Ask

View Details