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GBRR3 Antibody

Product Specifications

Background

GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel (By similarity) .

NCBI Gene ID

200959

Swiss Prot

A8MPY1

Accession Number

A8MPY1

Host

Rabbit

Reactivity

Human

Immunogen

This GBRR3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 35-63 amino acids from the N-terminal region of human GBRR3.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

54 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

GABRR3

NCBI Official Name

Gamma-aminobutyric acid receptor subunit rho-3

NCBI Organism

Homo sapiens

Background Reference 01

Craddock, N., et al. Mol. Psychiatry 15 (2) :146-153 (2010)

Background Reference 02

Gratacos, M., et al. Am. J. Med. Genet.Neuropsychiatr. Genet. 150B (6), 808-816 (2009) :

Background Reference 03

Muzny, D.M., et al. Nature 440 (7088) :1194-1198 (2006)

Background Reference 04

Alakuijala, A., et al. Brain Res. Dev. Brain Res. 154 (1) :15-23 (2005)

Other Product Names

Gamma-aminobutyric acid receptor subunit rho-3, GABA (A) receptor subunit rho-3, GABA (C) receptor, GABRR3

Tested Applications

WB

Physical Properties

Liquid

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