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NKAP Antibody

Product Specifications

Background

This gene encodes a protein that is involved in the activation of the ubiquitous transcription factor NF-kappaB. This protein is associated with the the histone deacetylase HDAC3 and with the Notch corepressor complex, and it thereby acts as a transcriptional repressor of Notch target genes. It is also required for alphabeta T cell development. A related pseudogene has been identified on chromosome X, while a related and intronless retrocopy, which has an intact CDS and may be functional, is located on chromosome 6.

NCBI Gene ID

79576

Swiss Prot

Q8N5F7

Accession Number

Q8N5F7

Host

Rabbit

Reactivity

Human

Immunogen

This NKAP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 387-415 amino acids from the C-terminal region of human NKAP.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Immunology, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

47 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

NKAP

NCBI Official Name

NF-kappa-B-activating protein

NCBI Organism

Homo sapiens

Background Reference 01

D'Addabbo, A., et al. Artif Intell Med 46 (2) :131-138 (2009)

Background Reference 02

Pajerowski, A.G., et al. Immunity 30 (5) :696-707 (2009)

Background Reference 03

Lamesch, P., et al. Genomics 89 (3) :307-315 (2007)

Background Reference 04

Chen, D., et al. Biochem. Biophys. Res. Commun. 310 (3) :720-724 (2003)

Other Product Names

NF-kappa-B-activating protein, NKAP

Tested Applications

WB

Protein ID

74728990

Physical Properties

Liquid

Frequently Asked Questions

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