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SENP6 Antibody

Product Specifications

Background

SENP6 (SUSP1) is a protease that deconjugates SUMO1, SUMO2 and SUMO3 from targeted proteins. This protein does not seem to be involved in the processing of full-length SUMO proteins to their mature conjugatable forms. SENP6 deconjugates SUMO1 from RXRA, leading to transcriptional activation. It may act preferentially on substrates containing 3 or more SUMO2 or SUMO3 moieties.

NCBI Gene ID

26054

Swiss Prot

Q9GZR1

Accession Number

Q9GZR1

Host

Rabbit

Reactivity

Human

Immunogen

This SENP6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1081-1112 amino acids from the C-terminal region of human SENP6.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=56-399

Calculated Molecular Weight

126 kDa

Fragment

Rabbit Ig

Symbol

SENP6

NCBI Official Name

Sentrin-specific protease 6

NCBI Organism

Homo sapiens

Background Reference 01

Ota, T., et al., Nat. Genet. 36 (1) :40-45 (2004) .

Background Reference 02

Strausberg, R.L., et al., Proc. Natl. Acad. Sci. U.S.A. 99 (26) :16899-16903 (2002) .

Background Reference 03

Kim, K.I., et al., J. Biol. Chem. 275 (19) :14102-14106 (2000) .

Other Product Names

Sentrin-specific protease 6, SUMO-1-specific protease 1, Sentrin/SUMO-specific protease SENP6, SENP6, KIAA0797, SSP1, SUSP1

Tested Applications

WB, IHC-P

Protein ID

119370526

Physical Properties

Liquid

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