SENP6 Antibody
Product Specifications
Background
SENP6 (SUSP1) is a protease that deconjugates SUMO1, SUMO2 and SUMO3 from targeted proteins. This protein does not seem to be involved in the processing of full-length SUMO proteins to their mature conjugatable forms. SENP6 deconjugates SUMO1 from RXRA, leading to transcriptional activation. It may act preferentially on substrates containing 3 or more SUMO2 or SUMO3 moieties.
NCBI Gene ID
26054
Swiss Prot
Q9GZR1
Accession Number
Q9GZR1
Host
Rabbit
Reactivity
Human
Immunogen
This SENP6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1081-1112 amino acids from the C-terminal region of human SENP6.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
126 kDa
Fragment
Rabbit Ig
Symbol
SENP6
NCBI Official Name
Sentrin-specific protease 6
NCBI Organism
Homo sapiens
Background Reference 01
Ota, T., et al., Nat. Genet. 36 (1) :40-45 (2004) .
Background Reference 02
Strausberg, R.L., et al., Proc. Natl. Acad. Sci. U.S.A. 99 (26) :16899-16903 (2002) .
Background Reference 03
Kim, K.I., et al., J. Biol. Chem. 275 (19) :14102-14106 (2000) .
Other Product Names
Sentrin-specific protease 6, SUMO-1-specific protease 1, Sentrin/SUMO-specific protease SENP6, SENP6, KIAA0797, SSP1, SUSP1
Tested Applications
WB, IHC-P
Protein ID
119370526
Physical Properties
Liquid
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