SLC12A6 Antibody

Product Specifications

Background

This gene is a member of the K-Cl cotransporter (KCC) family. K-Cl cotransporters are integral membrane proteins that lower intracellular chloride concentrations below the electrochemical equilibrium potential. The proteins encoded by this gene are activated by cell swelling induced by hypotonic conditions. Alternate splicing results in multiple transcript variants encoding different isoforms. Mutations in this gene are associated with agenesis of the corpus callosum with peripheral neuropathy.

NCBI Gene ID

9990

Swiss Prot

Q9UHW9

Accession Number

Q9UHW9

Host

Rabbit

Reactivity

Human

Immunogen

This SLC12A6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 13-42 amino acids from the N-terminal region of human SLC12A6.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

128 kDa

Fragment

Rabbit Ig

Symbol

SLC12A6

NCBI Official Name

Solute carrier family 12 member 6

NCBI Organism

Homo sapiens

Background Reference 01

Rinehart, J., et al. Cell 138 (3) :525-536 (2009)

Background Reference 02

Rudnik-Schoneborn, S., et al. Neuropediatrics 40 (3) :129-133 (2009)

Background Reference 03

De Krom, M., et al. Biol. Psychiatry 65 (7) :625-630 (2009)

Background Reference 04

Moser, D., et al. Neuropsychopharmacology 34 (2) :458-467 (2009)

Other Product Names

Solute carrier family 12 member 6, Electroneutral potassium-chloride cotransporter 3, K-Cl cotransporter 3, SLC12A6, KCC3

Tested Applications

WB, IHC-P

Protein ID

27151690

Physical Properties

Liquid

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

MBS6356161-01 0.1 mL

TMC6, NT (TMC6, EVER1, EVIN1, Transmembrane channel-like protein 6, Epidermodysplasia verruciformis protein 1, Protein LAK-4) (MaxLight 750)

Ask

View Details

MBS6356161-02 5x 0.1 mL

TMC6, NT (TMC6, EVER1, EVIN1, Transmembrane channel-like protein 6, Epidermodysplasia verruciformis protein 1, Protein LAK-4) (MaxLight 750)

Ask

View Details

MBS1138403-01 0.05 mg (E-Coli)

Recombinant Saccharomyces cerevisiae H/ACA ribonucleoprotein complex non-core subunit NAF1 (NAF1)

Ask

View Details

MBS1138403-02 0.05 mg (Yeast)

Recombinant Saccharomyces cerevisiae H/ACA ribonucleoprotein complex non-core subunit NAF1 (NAF1)

Ask

View Details

MBS1138403-03 0.05 mg (Baculovirus)

Recombinant Saccharomyces cerevisiae H/ACA ribonucleoprotein complex non-core subunit NAF1 (NAF1)

Ask

View Details

MBS1138403-04 0.2 mg (E-Coli)

Recombinant Saccharomyces cerevisiae H/ACA ribonucleoprotein complex non-core subunit NAF1 (NAF1)

Ask

View Details