MST1 Antibody
Product Specifications
Background
The protein encoded by this gene contains four kringle domains and a serine protease domain, similar to that found in hepatic growth factor. Despite the presence of the serine protease domain, the encoded protein may not have any proteolytic activity. The receptor for this protein is RON tyrosine kinase, which upon activation stimulates ciliary motility of ciliated epithelial lung cells. This protein is secreted and cleaved to form an alpha chain and a beta chain bridged by disulfide bonds.
NCBI Gene ID
4485
Swiss Prot
P26927
Accession Number
P26927
Host
Rabbit
Reactivity
Human
Immunogen
This MST1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 454-483 amino acids from the C-terminal region of human MST1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Immunology
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
80 kDa
Fragment
Rabbit Ig
Symbol
MST1
NCBI Official Name
Hepatocyte growth factor-like protein
NCBI Organism
Homo sapiens
Background Reference 01
Latiano, A., et al. Inflamm. Bowel Dis. 16 (7) :1108-1117 (2010)
Background Reference 02
Morgan, A.R., et al. Hum. Immunol. 71 (6) :602-609 (2010)
Background Reference 03
Qiao, M., et al. Mol. Cell 38 (4) :512-523 (2010)
Background Reference 04
McGovern, D.P., et al. Nat. Genet. 42 (4) :332-337 (2010)
Other Product Names
Hepatocyte growth factor-like protein, Macrophage stimulatory protein, Macrophage-stimulating protein, MSP, Hepatocyte growth factor-like protein alpha chain, Hepatocyte growth factor-like protein beta chain, MST1, D3F15S2, DNF15S2, HGFL
Tested Applications
WB, IHC-P, Flow
Protein ID
147744563
Physical Properties
Liquid
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