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SFRP2 Antibody

Product Specifications

Background

This gene encodes a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. SFRPs act as soluble modulators of Wnt signaling. Methylation of this gene is a potential marker for the presence of colorectal cancer. [provided by RefSeq].

NCBI Gene ID

6423

Swiss Prot

Q96HF1

Accession Number

Q96HF1

Host

Rabbit

Reactivity

Human

Immunogen

This SFRP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 263-292 amino acids from the C-terminal region of human SFRP2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

33 kDa

Fragment

Rabbit Ig

Symbol

SFRP2

NCBI Official Name

Secreted frizzled-related protein 2

NCBI Organism

Homo sapiens

Background Reference 01

Von Marschall, Z., et al. Biochem. Biophys. Res. Commun. 400 (3) :299-304 (2010)

Background Reference 02

Pehlivan, S., et al. Cancer Genet. Cytogenet. 201 (2) :128-132 (2010)

Background Reference 03

Kohno, H., et al. Oncol. Rep. 24 (2) :423-431 (2010)

Background Reference 04

Yamamura, S., et al. Mol. Cancer Ther. 9 (6) :1680-1687 (2010)

Other Product Names

Secreted frizzled-related protein 2, FRP-2, sFRP-2, Secreted apoptosis-related protein 1, SARP-1, SFRP2, FRP2, SARP1

Tested Applications

WB, IHC-P

Protein ID

61216828

Physical Properties

Liquid

Curated Selection

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