PARP2 Antibody
Product Specifications
Background
Parp2 is involved in the base excision repair (BER) pathway, by catalyzing the poly (ADP-ribosyl) ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks.
NCBI Gene ID
11546
Swiss Prot
O88554
Accession Number
O88554
Host
Rabbit
Reactivity
Mouse
Immunogen
This PARP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 306-336 amino acids from the C-terminal region of human PARP2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=56-362
Calculated Molecular Weight
63 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
Parp2
NCBI Official Name
Poly [ADP-ribose] polymerase 2
NCBI Organism
Mus musculus
Background Reference 01
Brunyanszki, A., et al. J. Invest. Dermatol. 130 (11) :2629-2637 (2010)
Background Reference 02
Toller, I.M., et al. Cancer Res. 70 (14) :5912-5922 (2010)
Background Reference 03
Nicolas, L., et al. Oncogene 29 (19) :2877-2883 (2010)
Background Reference 04
Li, X., et al. J. Neurochem. 113 (4) :1012-1022 (2010)
Other Product Names
Poly [ADP-ribose] polymerase 2, PARP-2, mPARP-2, ADP-ribosyltransferase diphtheria toxin-like 2, ARTD2, NAD (+) ADP-ribosyltransferase 2, ADPRT-2, Poly[ADP-ribose] synthase 2, pADPRT-2, Parp2, Adprt2, Adprtl2, Aspartl2
Tested Applications
WB
Physical Properties
Liquid
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