ACTN3 Antibody

Product Specifications

Background

Alpha-actinin is an actin-binding protein with multiple roles in different cell types. This gene expression is limited to skeletal muscle. It is localized to the Z-disc and analogous dense bodies, where it helps to anchor the myofibrillar actin filaments

NCBI Gene ID

Swiss Prot

Q08043

Accession Number

Q08043

Host

Rabbit

Reactivity

Human

Immunogen

This ACTN3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 409-437 amino acids from the Central region of human ACTN3.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

103 kDa

Fragment

Rabbit Ig

Symbol

ACTN3

NCBI Official Name

Alpha-actinin-3

NCBI Organism

Homo sapiens

Background Reference 01

Rodriguez-Romo, G., et al. Eur. J. Appl. Physiol. 110 (6) :1099-1106 (2010)

Background Reference 02

Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)

Background Reference 03

Berman, Y., et al. Physiology (Bethesda) 25 (4) :250-259 (2010)

Background Reference 04

Ruiz, J.R., et al. ScandMed Sci Sports (2010) In press :

Other Product Names

Alpha-actinin-3, Alpha-actinin skeletal muscle isoform 3, F-actin cross-linking protein, ACTN3

Tested Applications

WB, IHC-P

Protein ID

215273967

Physical Properties

Liquid

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