SENP1 Antibody
Product Specifications
Background
SENP1 is a protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SUMO1, SUMO2 and SUMO3 to their mature forms and deconjugation of SUMO1, SUMO2 and SUMO3 from targeted proteins. SENP deconjugates SUMO1 from HIPK2 and from HDAC1, which decreases the transcriptional repression activity of the latter.
NCBI Gene ID
29843
Swiss Prot
Q9P0U3
Accession Number
Q9P0U3
Host
Rabbit
Reactivity
Human
Immunogen
This SENP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 560-590 amino acids from the C-terminal region of human SENP1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
73 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
SENP1
NCBI Official Name
Sentrin-specific protease 1
NCBI Organism
Homo sapiens
Background Reference 01
Gong, L., et al., J. Biol. Chem. 275 (5) :3355-3359 (2000) .
Background Reference 02
Bailey, D., et al., J. Gen. Virol. 83 (Pt 12), 2951-2964 (2002) .
Other Product Names
Sentrin-specific protease 1, Sentrin/SUMO-specific protease SENP1, SENP1
Tested Applications
WB
Protein ID
215273882
Physical Properties
Liquid
Curated Selection
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