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SENP1 Antibody

Product Specifications

Background

SENP1 is a protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SUMO1, SUMO2 and SUMO3 to their mature forms and deconjugation of SUMO1, SUMO2 and SUMO3 from targeted proteins. SENP deconjugates SUMO1 from HIPK2 and from HDAC1, which decreases the transcriptional repression activity of the latter.

NCBI Gene ID

29843

Swiss Prot

Q9P0U3

Accession Number

Q9P0U3

Host

Rabbit

Reactivity

Human

Immunogen

This SENP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 28-59 amino acids from the N-terminal region of human SENP1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

73 kDa

Fragment

Rabbit Ig

Symbol

SENP1

NCBI Official Name

Sentrin-specific protease 1

NCBI Organism

Homo sapiens

Background Reference 01

Gong, L., et al., J. Biol. Chem. 275 (5) :3355-3359 (2000) . Bailey, D., et al., J. Gen. Virol. 83 (Pt 12), 2951-2964 (2002) .

Other Product Names

Sentrin-specific protease 1, Sentrin/SUMO-specific protease SENP1, SENP1

Tested Applications

WB, IHC-P

Protein ID

215273882

Physical Properties

Liquid

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