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SFRS7 Antibody

Product Specifications

Background

The protein encoded by this gene is a member of the serine/arginine (SR) -rich family of pre-mRNA splicing factors, which constitute part of the spliceosome. Each of these factors contains an RNA recognition motif (RRM) for binding RNA and an RS domain for binding other proteins. The RS domain is rich in serine and arginine residues and facilitates interaction between different SR splicing factors. In addition to being critical for mRNA splicing, the SR proteins have also been shown to be involved in mRNA export from the nucleus and in translation. Two transcript variants encoding different isoforms have been found for this gene.

NCBI Gene ID

6432

Swiss Prot

Q16629

Accession Number

Q16629

Host

Rabbit

Reactivity

Human

Immunogen

This SFRS7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 69-98 amino acids from the N-terminal region of human SFRS7.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine, Mouse

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

27 kDa

Fragment

Rabbit Ig

Symbol

SRSF7

NCBI Official Name

Serine/arginine-rich splicing factor 7

NCBI Organism

Homo sapiens

Background Reference 01

Kimura, T., et al. Med Mol Morphol 43 (3) :145-157 (2010)

Background Reference 02

Escudero-Paunetto, L., et al. Virology 401 (2) :155-164 (2010)

Background Reference 03

Manley, J.L., et al. Genes Dev. 24 (11) :1073-1074 (2010)

Background Reference 04

Valente, S.T., et al. Mol. Cell 36 (2) :279-289 (2009)

Other Product Names

Serine/arginine-rich splicing factor 7, Splicing factor 9G8, Splicing factor, arginine/serine-rich 7, SRSF7, SFRS7

Tested Applications

WB, IHC-P

Protein ID

3929380

Physical Properties

Liquid

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