PRSS7 Antibody

Product Specifications

Background

This gene encodes an enzyme that converts the pancreatic proenzyme trypsinogen to trypsin, which activates other proenzymes including chymotrypsinogen and procarboxypeptidases. The precursor protein is cleaved into two chains that form a heterodimer linked by a disulfide bond. This protein is a member of the trypsin family of peptidases. Mutations in this gene cause enterokinase deficiency, a malabsorption disorder characterized by diarrhea and failure to thrive.

NCBI Gene ID

5651

Swiss Prot

P98073

Accession Number

P98073

Host

Rabbit

Reactivity

Human

Immunogen

This PRSS7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 964-994 amino acids from the C-terminal region of human PRSS7.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

113 kDa

Fragment

Rabbit Ig

Symbol

TMPRSS15

NCBI Official Name

Enteropeptidase

NCBI Organism

Homo sapiens

Background Reference 01

Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :

Background Reference 02

Nakanishi, J., et al. J. Invest. Dermatol. 130 (4) :944-952 (2010)

Background Reference 03

Vilen, S.T., et al. Exp. Cell Res. 314 (4) :914-926 (2008)

Background Reference 04

Imamura, T., et al. Am. J. Physiol. Gastrointest. Liver Physiol. 285 (6), G1235-G1241 (2003) :

Other Product Names

Enteropeptidase, Enterokinase, Serine protease 7, Transmembrane protease serine 15, Enteropeptidase non-catalytic heavy chain, Enteropeptidase catalytic light chain, TMPRSS15, ENTK, PRSS7