SFTPA2B Antibody

Product Specifications

Background

This gene is one of several genes encoding pulmonary-surfactant associated proteins (SFTPA) located on chromosome 10. Mutations in this gene and a highly similar gene located nearby, which affect the highly conserved carbohydrate recognition domain, are associated with idiopathic pulmonary fibrosis. The current version of the assembly displays only a single centromeric SFTPA gene pair rather than the two gene pairs shown in the previous assembly which were thought to have resulted from a duplication.

NCBI Gene ID

729238

Swiss Prot

Q8IWL1

Accession Number

Q8IWL1

Host

Rabbit

Reactivity

Human

Immunogen

This SFTPA2B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 174-202 amino acids from the C-terminal region of human SFTPA2B.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

26 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

SFTPA2

NCBI Official Name

Pulmonary surfactant-associated protein A2

NCBI Organism

Homo sapiens

Background Reference 01

Silveyra, P., et al. Am. J. Physiol. Lung Cell Mol. Physiol. 299 (4), L523-L534 (2010) :

Background Reference 02

Maitra, M., et al. J. Biol. Chem. 285 (29) :22103-22113 (2010)

Background Reference 03

Wang, G., et al. J. Biol. Chem. 285 (16) :11998-12010 (2010)

Background Reference 04

El Saleeby, C.M., et al. J. Pediatr. 156 (3) :409-414 (2010)

Other Product Names

Pulmonary surfactant-associated protein A2, PSP-A, PSPA, SP-A, SP-A2, 35 kDa pulmonary surfactant-associated protein, Alveolar proteinosis protein, Collectin-5, SFTPA2, COLEC5, PSAP, SFTP1, SFTPA, SFTPA2B