ITGA5 Antibody

Product Specifications

Background

The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes the integrin alpha 5 chain. Alpha chain 5 undergoes post-translational cleavage in the extracellular domain to yield disulfide-linked light and heavy chains that join with beta 1 to form a fibronectin receptor. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling. [provided by RefSeq].

NCBI Gene ID

3678

Swiss Prot

P08648

Accession Number

P08648

Host

Rabbit

Reactivity

Human

Immunogen

This ITGA5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 575-602 amino acids from the Central region of human ITGA5.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

115 kDa

Fragment

Rabbit Ig

Symbol

ITGA5

NCBI Official Name

Integrin alpha-5

NCBI Organism

Homo sapiens

Background Reference 01

Hutton, M.L., et al. Infect. Immun. 78 (11) :4523-4531 (2010)

Background Reference 02

Fang, Z., et al. J. Cell. Biochem. 110 (5) :1130-1141 (2010)

Background Reference 03

Lobert, V.H., et al. Dev. Cell 19 (1) :148-159 (2010)

Background Reference 04

Caicedo-Carvajal, C.E., et al. PLoS ONE (7), E11830 (2010) :

Other Product Names

Integrin alpha-5, CD49 antigen-like family member E, Fibronectin receptor subunit alpha, Integrin alpha-F, VLA-5, CD49e, Integrin alpha-5 heavy chain, Integrin alpha-5 light chain, ITGA5, FNRA