HGCN5 Antibody

Product Specifications

Background

KAT2A, or GCN5, is a histone acetyltransferase (HAT) that functions primarily as a transcriptional activator. It also functions as a repressor of NF-kappa-B (see MIM 164011) by promoting ubiquitination of the NF-kappa-B subunit RELA (MIM 164014) in a HAT-independent manner (Mao et al., 2009 [PubMed 19339690]) .

NCBI Gene ID

2648

Swiss Prot

Q92830

Accession Number

Q92830

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This hGCN5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 807-837 amino acids from the C-terminal region of human hGCN5.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

94 kDa

Fragment

Rabbit Ig

Symbol

KAT2A

NCBI Official Name

Histone acetyltransferase KAT2A

NCBI Organism

Homo sapiens

Background Reference 01

Terreni, M., et al. Retrovirology 7, 18 (2010) :

Background Reference 02

Atanassov, B.S., et al. Mol. Cell 35 (3) :352-364 (2009)

Background Reference 03

Kelly, T.J., et al. J. Biol. Chem. 284 (30) :19945-19952 (2009)

Background Reference 04

Mao, X., et al. Genes Dev. 23 (7) :849-861 (2009)

Other Product Names

Histone acetyltransferase KAT2A, General control of amino acid synthesis protein 5-like 2, Histone acetyltransferase GCN5, HsGCN5, Lysine acetyltransferase 2A, STAF97, KAT2A, GCN5, GCN5L2, HGCN5