NKD2 Antibody
Product Specifications
Background
In the mouse, Nkd is a Dishevelled (see DVL1; MIM 601365) -binding protein that functions as a negative regulator of the Wnt (see WNT1; MIM 164820) -beta-catenin (see MIM 116806) -Tcf (see MIM 602272) signaling pathway.
NCBI Gene ID
85409
Swiss Prot
Q969F2
Accession Number
Q969F2
Host
Rabbit
Reactivity
Human
Immunogen
This NKD2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 366-393 amino acids from the C-terminal region of human NKD2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
50 kDa
Fragment
Rabbit Ig
Symbol
NKD2
NCBI Official Name
Protein naked cuticle homolog 2
NCBI Organism
Homo sapiens
Background Reference 01
Hu, T., et al. J. Biol. Chem. 285 (18) :13561-13568 (2010)
Background Reference 02
Ding, W., et al. Proc. Natl. Acad. Sci. U.S.A. 105 (36) :13433-13438 (2008)
Background Reference 03
Li, C., et al. Mol. Biol. Cell 18 (8) :3081-3093 (2007)
Background Reference 04
Adamowicz, M., et al. Genes Chromosomes Cancer 45 (9) :829-838 (2006)
Other Product Names
Protein naked cuticle homolog 2, Naked-2, hNkd2, NKD2
Tested Applications
WB, IHC-P, IF, Flow
Protein ID
74716653
Physical Properties
Liquid
Curated Selection
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