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HCG_1646420 Antibody

Product Specifications

Background

This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions.

NCBI Gene ID

644672

Swiss Prot

C9JDP6

Accession Number

C9JDP6

Host

Rabbit

Reactivity

Human

Immunogen

This hCG_1646420 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 99-128 amino acids from the Central region of human hCG_1646420.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

25 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

CLDN25

NCBI Official Name

Putative claudin-25

NCBI Organism

Homo sapiens

Background Reference 01

Lal-Nag, M., et al. Genome Biol. 10 (8), 235 (2009) :

Background Reference 02

Krause, G., et al. Biochim. Biophys. Acta 1778 (3) :631-645 (2008)

Background Reference 03

Katoh, M., et al. Int. J. Mol. Med. 11 (6) :683-689 (2003)

Background Reference 04

Venter, J.C., et al. Science 291 (5507) :1304-1351 (2001)

Other Product Names

Putative claudin-25, CLDN25

Tested Applications

WB

Physical Properties

Liquid

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