TRIM69 Antibody
Product Specifications
Background
This gene encodes a member of the RING-B-box-coiled-coil (RBCC) family and encodes a protein with an N-terminal RING finger motif, a PRY domain and a C-terminal SPRY domain. The mouse ortholog of this gene is specifically expressed in germ cells at the round spermatid stages during spermatogenesis and, when overexpressed, induces apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been described. It may play a role in apoptosis (By similarity) .
NCBI Gene ID
140691
Swiss Prot
Q86WT6
Accession Number
Q86WT6
Host
Rabbit
Reactivity
Mouse
Immunogen
This TRIM69 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 101-129 amino acids from the N-terminal region of human TRIM69.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Cell Cycle, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
57 kDa
Fragment
Rabbit Ig
Symbol
TRIM69
NCBI Official Name
E3 ubiquitin-protein ligase TRIM69
NCBI Organism
Homo sapiens
Background Reference 01
Shimada, M., et al. Hum. Genet. 128 (4) :433-441 (2010)
Background Reference 02
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Background Reference 03
Shyu, H.W., et al. Exp. Cell Res. 287 (2) :301-313 (2003)
Background Reference 04
Shyu, H.W., et al. Mech. Dev. 108 (1-2), 213-216 (2001) :
Other Product Names
E3 ubiquitin-protein ligase TRIM69, 632-, RFP-like domain-containing protein trimless, RING finger protein 36, Tripartite motif-containing protein 69, TRIM69, RNF36
Tested Applications
WB, IHC-P
Protein ID
229462760
Physical Properties
Liquid