TXNL2 Antibody
Product Specifications
Background
GLRX3 is a critical negative regulator of cardiac hypertrophy and a positive inotropic regulator (By similarity) . May play a role in regulating the function of the thioredoxin system. Does not posses any thyoredoxin activity since it lacks the conserved motif that is essential for catalytic activity.
NCBI Gene ID
10539
Swiss Prot
O76003
Accession Number
O76003
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This TXNL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 81-110 amino acids from the N-terminal region of human TXNL2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
37 kDa
Fragment
Rabbit Ig
Symbol
GLRX3
NCBI Official Name
Glutaredoxin-3
NCBI Organism
Homo sapiens
Background Reference 01
Ohayon, A., et al. J. Histochem. Cytochem. 58 (9) :799-806 (2010)
Background Reference 02
Haunhorst, P., et al. Biochem. Biophys. Res. Commun. 394 (2) :372-376 (2010)
Background Reference 03
Ohayon, A., et al.Immunotoxicol 7 (1) :8-14 (2010)
Background Reference 04
Cha, M.K., et al. Cancer Epidemiol 33 (3-4), 281-287 (2009) :
Other Product Names
Glutaredoxin-3, PKC-interacting cousin of thioredoxin, PICOT, PKC-theta-interacting protein, PKCq-interacting protein, Thioredoxin-like protein 2, GLRX3, PICOT, TXNL2
Tested Applications
WB, Flow
Physical Properties
Liquid
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