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CFD Antibody

Product Specifications

Background

The protein encoded by this gene is a member of the trypsin family of peptidases. The encoded protein is a component of the alternative complement pathway best known for its role in humoral suppression of infectious agents. This protein is also a serine protease that is secreted by adipocytes into the bloodstream. Finally, the encoded protein has a high level of expression in fat, suggesting a role for adipose tissue in immune system biology.

NCBI Gene ID

1675

Swiss Prot

P00746

Accession Number

P00746

Host

Rabbit

Reactivity

Human

Immunogen

This CFD antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 68-99 amino acids from the N-terminal region of human CFD.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Immunology

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Pig, Bovine

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=56-222

Calculated Molecular Weight

27 kDa

Fragment

Rabbit IgG

Applications Notes

For WB starting dilution is: 1:2000

Symbol

CFD

NCBI Official Name

Complement factor D

NCBI Organism

Homo sapiens

Background Reference 01

Bailey, S.D., et al. Diabetes Care (2010) In press :

Background Reference 02

Hietaharju, A., et al. Eur. J. Neurol. 17 (2) :332-334 (2010)

Background Reference 03

Talmud, P.J., et al. Am. J. Hum. Genet. 85 (5) :628-642 (2009)

Background Reference 04

Ciprandi, G., et al. Int. Immunopharmacol. 9 (12) :1460-1463 (2009)

Other Product Names

Complement factor D, Adipsin, C3 convertase activator, Properdin factor D, CFD, DF, PFD

Tested Applications

WB, IHC-P

Protein ID

158515408

Physical Properties

Liquid

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