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Maspin Antibody

Product Specifications

Background

SERPINB5 is a tumor suppressor. It blocks the growth, invasion, and metastatic properties of mammary tumors. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity.

NCBI Gene ID

5268

Swiss Prot

P36952

Accession Number

P36952

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This Maspin antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 94-123 amino acids from the Central region of human Maspin.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=56-219

Calculated Molecular Weight

42 kDa

Fragment

Rabbit Ig

Symbol

SERPINB5

NCBI Official Name

Serpin B5

NCBI Organism

Homo sapiens

Background Reference 01

Kim, J., et al. Tumour Biol. 31 (5) :471-476 (2010)

Background Reference 02

Juengel, E., et al. WorldUrol 28 (4) :465-471 (2010)

Background Reference 03

Besgen, P., et al. J. Immunol. 184 (9) :5392-5402 (2010)

Background Reference 04

Fung, C.L., et al. Histopathology 56 (3) :319-330 (2010)

Other Product Names

Serpin B5, Maspin, Peptidase inhibitor 5, PI-5, SERPINB5, PI5

Tested Applications

WB, IHC-P, IF

Protein ID

229462757

Physical Properties

Liquid

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